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解読されたシダゲノム:環境の持続可能性への希望

Unlocking the genetic information of a fern could provide us potential solutions to multiple issues faced by our 惑星

In ゲノム シーケンシング、 DNA sequencing is done to determine the order of nucleotides in every specific DNA molecule. This exact order is of value to be able to understand the type of genetic information carried in the DNA. Since genes encode for protein which are responsible for most body functions, this information can help to understand the effect of their function in the body. Sequencing complete ゲノム of an organism i.e. all of its DNA is a complex and challenging task and has to be done bit by bit by breaking DNA into smaller pieces, sequencing them and then putting it all together. For example, the complete human ゲノム was sequenced in 2003 took 13 years and a total cost of USD 3 billion. With advancement in technology ゲノム can be sequenced relatively faster and at a lower cost using methods like Sanger sequencing and Next-generation sequencing. Once a genome is sequenced and decoded, unlimited possibilities open up for identifying potential areas of biological research and making progress towards targeted application development.

A team of 40 researchers from Cornell University and around the world have sequenced the full ゲノム 水の 羊歯 アゾラフィリクロイデスと呼ばれる1,2. This fern is commonly seen to be growing in warmer temperatures and tropical regions of the world. The project of unravelling genomic secrets of the fern has been in the pipeline for a while and was backed by funds of USD 22,160 from 123 backers through a crowdfunding site called Experiment.com. Researchers eventually received funding to carry out the sequencing from Beijing Genomics Institute in collaboration with Utrecht University. This tiny floating fern species which fits over a finger nail has a genome size of .75 gigabases (or billion base pairs). Ferns are known to have large ゲノム, average of 12 gigabases in size, however none of the larger fern genomes have been decoded so far. Such an elaborate project was aimed at providing clues on what could be the potential of this fern.

Many interesting aspects of fern Azolla have been uncovered upon this ゲノム sequencing study published in 自然植物 and have provided direction for future research on potential areas in which this fern can be beneficial. The fern Azolla was widespread and growing almost 50 million years ago on this 惑星 around the Arctic Ocean. During that time Earth was also warmer compared to current conditions and this fern was thought to play a significant role in keeping the 惑星 cooler by capturing around 10 trillion tons of carbon dioxide from the atmosphere over the course of 1 million years. Here we see a potential role for this fern in combating and protecting our 惑星 from global warming resulted by climate change.

The fern is also thought to play an important role in nitrogen fixation, a process which combines free nitrogen (N2) in the atmosphere – an inert gas available abundantly in air – with other chemical elements to create more reactive nitrogen-based compounds e.g. ammonia, nitrates etc which can then be used in various applications like fertilizer for agriculture purposes. ゲノム data tells us about a symbiotic relationship (mutual benefit) of this fern with a cyanobacteria named Nostoc azollae. The fern leaf host these cyanobacteria in tiny holes and these bacteria fix nitrogen thereby producing 酸素 シダとその周辺の成長する植物が使用できるもの。 次に、シアノ 細菌 gather energy through the plant photosynthesis when the fern provides it fuel. Therefore, this fern could be possibly used as a natural green fertilizer and possibly eliminate usage of nitrogen fertilizers propagating more sustainable agricultures practises. Authors say that having both the ゲノム of cyanobacteria and now the fern, research can be focused on developing and adopting such sustainable practises. Interestingly, fern Azolla has already been added in rice paddies as green manure by Asian farmers for more than 1000 years.

研究者たちはまた、シダの重要な自然修飾(殺虫剤)遺伝子を特定しました。これは、昆虫抵抗性を提供する能力があると見られています。 この遺伝子はワタ植物に移されると、昆虫からの大規模な保護を提供します。 この「殺虫性」遺伝子は、バクテリアからシダに移されるか「贈与される」と考えられており、シダの系統の非常に特殊な構成要素であると見られています。つまり、世代から世代へと受け継がれています。 昆虫からの潜在的な保護の発見は、農業の実践に強い影響を与えるに違いありません。

This study shows that ‘pure science’ of unravelling first ever genomic information from ferns is a major step in the direction of uncovering and understanding crucial plant genes. It also helps in a better understanding of the evolutionary history of ferns i.e. how their features have evolved over the generations. Understanding of plants is very crucial to explore and comprehend how flora and fauna exist together amicably on our 惑星 and such research should be given importance rather than labelling it as something which is not significant enough. After sequencing Azolla filiculoides and Salvinia cucullata, more than 10 fern species are already in pipeline for further research.

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{引用元のリストにある以下のDOIリンクをクリックすると、元の研究論文を読むことができます}

ソース

1. Fay-Wei L et al. 2018. Fern ゲノム elucidate land plant evolution and cyanobacterial symbioses. 自然植物。 4(7)。 https://doi.org/10.1038/s41477-018-0188-8

2.ファーンベース https://www.fernbase.org/。 [18年2018月XNUMX日にアクセス]。

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