科学者たちは、動物モデルの不安を軽減する抹茶粉末と抽出物の効果を初めて実証しました。 抹茶は、不安を和らげ、気分を高めるための安全で自然な代替品です。
気分と 不安 disorders are becoming commonplace in our fast-paced and often stressful lives. 不安 disorders and fear has been linked to disturbance in dopaminergic and serotonergic systems in our brain. 不安 symptoms also increases risk of other medical disorders and affects overall wellbeing of a person. Anxiolytic (or antianxiety) agents like benzodiazepines and serotonin inhibitors are generally used for treatment as they reduce or inhibit 不安. However, they have many side effects, sometimes even adverse, and they also increase dependency. Safer, natural alternative need to be developed for 不安 管理。
日本では古くから「抹茶」がさまざまな薬用として利用されてきました。抹茶は、樹木の新葉の力を細かく粉砕したものです。 カメリアシネンシス 日陰でのみ成長することが許可されています。 抹茶パウダーを使って作る 抹茶 by adding it directly to hot water. It is also used for adding flavour to food. Matcha お茶 is different from regular green tea in its content mainly because of differences cultivation and processing. カメリアシネンシス 植物はL-テアニン、エピガロカテキンガレート(EGCG)、カフェイン、ビタミン、アミノ酸が豊富であるため、抹茶を摂取すると、これらの生物活性物質に付随するいくつかの利点が得られます。 日本では、肌の調子を整えたり、リラックスしたり、治療したりするためによく使われています。 ただし、上記の主張を裏付けるために利用できる科学的証拠は非常に限られています。 また、抹茶パウダーが行動面に与える影響については、これまで調査されていませんでした。
に発表された研究 機能性食品ジャーナル has investigated and demonstrated the effects of Matcha お茶 powder, hot water extract and ethanol extract for 抗不安 activity in an animal model (here, mice). Researchers conducted an elevated plus maze (EPM) test in healthy animals. EPM involves use of an elevated plus-shaped platform which has two open arms and two closed arms with walls around it. It is a commonly used anxiety test in which animal subjects which are anxious try to stay on the safe area of the plus where they cannot fall off.
The animals were orally administered Matcha powder and extract or fractions dissolved in water. Results showed that the animals who had consumed Matcha had reduced 不安. The strongest effect was seen in Matcha extract derived using 80% ethanol when compared to extract derived from hot water. This meant that poor water-solubility of Matcha has better 抗不安 effect than when it was easily water soluble. The ethanol extract was fractioned further into hexane soluble, ethyl acetate soluble and water-soluble fractions which exhibited similar results. Behavioural analysis showed that Matcha power and extract reduce 不安 by activating dopamine D1 and serotonin 5-HT1A receptors which are closely linked to anxious behaviour.
The current study conducted on mice demonstrates that Matcha お茶 powder and extract have a positive calming effect and reduce anxiety by activating dopaminergic and serotonergic systems in the brain. Matcha is a safe and natural alternative for alleviating anxiety.
***
{引用元のリストにある以下のDOIリンクをクリックすると、元の研究論文を読むことができます}
ソース
Kurauchi, Y. et al. 2019. Anxiolytic activities of Matcha お茶 powder, extracts, and fractions in mice: Contribution of dopamine D1 receptor- and serotonin 5-HT1A receptor-mediated mechanisms. Journal of Functional Foods. https://doi.org/10.1016/j.jff.2019.05.046