Recent research studying almost 44,000 men and women finds that higher levels of ビタミンC & ビタミン E in the diet are associated with lower risk of Parkinson’s Disease1.
ビタミン C and E are antioxidants2。 酸化防止剤は、フリーラジカルとして知られている反応性の高い分子によって引き起こされる酸化ストレスを打ち消します2。 酸化ストレスには、日光、大気汚染、タバコの煙、運動などのさまざまな原因があります2. Oxidative stress can cause cell damage (through damage to molecules in the body) and can contribute to many diseases such as cancer, heart disease, diabetes, Alzheimer’s disease, Parkinson’s 病気 and even eye diseases2。 したがって、抗酸化物質は、分子の損傷を防ぎ、細胞の健康を維持するのに有益である可能性があります。
A recent Swedish study explored the effects of certain dietary factors on the incidence of development of パーキンソン病 (PD) in almost 44,000 men and women1. These factors included dietary intake of ビタミン C, ビタミン E and beta-carotene1。 これらの特定の微量栄養素の摂取量を、グループ内のPDの発生率と比較しました1.
ベータカロチンはPDリスクと相関関係がありませんでした1. However, intake of ビタミン C and E was inversely correlated to the risk of PD1 これらの抗酸化物質がPDの発生率を低下させる神経保護効果を提供したことを示しています。
This study may allow the inference that it may be beneficial to increase these ビタミン in the diet to reduce risk of PD, but it does not necessarily mean that the association seen was caused by the intake of these ビタミン, as people ingesting more of these ビタミン might just have healthier diets and lifestyles. It may be the case that there was a causal relationship but this is hard to prove from an association study. There could also be a non-causal relationship; supporting this is the finding from an older study comparing levels of antioxidants in the blood of PD patients which found no evidence that antioxidants contributed to onset or progression of PD3. Lastly, both theories may be true, where ビタミン C and E in diet played a minor role. Regardless, the overall message of intaking enough vitamin C (such as through eating oranges and strawberries) and ビタミン E (such as through eating nuts and seeds) is probably conducive to good health.
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参照：
- Hantikainen E., Lagerros Y., et al 2021. Dietary Antioxidants and the Risk of Parkinson 病気. The Swedish National March Cohort. Neurology Feb 2021, 96 (6) e895-e903; DOI: https://doi.org/10.1212/WNL.0000000000011373
- NIH2021。酸化防止剤：詳細。 オンラインで入手可能 https://www.nccih.nih.gov/health/antioxidants-in-depth
- King D.、Playfer J.、およびRoberts N.、1992年。パーキンソン病の高齢患者におけるビタミンA、C、およびEの濃度。PostgradMedJ（1992）68,634-637。 オンラインで入手可能 https://pmj.bmj.com/content/postgradmedj/68/802/634.full.pdf
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